We analyze the necrosis growth due to thermal coagulation induced by laserlight absorption and limited by heat diffusion into the surrounding livetissue. The tissue is assumed to contain a certain tumor in the undamagedtissue whereof the blood perfusion rate does not change during the action. Bycontrast, the normal tissue responds strongly to increase in the tissuetemperature and the blood perfusion rate can grow by tenfold. We study indetail the necrosis formation under conditions typical for a real course ofthermal therapy treatment, the duration of the action is taken about 5 minuteswhen a necrosis domain of size about or above 1 cm is formed. In particular, ifthe tumor size is sufficiently large, it exceeds 1 cm, and the tissue responseis not too delayed, the delay time does not exceed 1 min, then there areconditions under which the relative volume of the damaged normal tissue issmall in comparison with the tumor volume after the tumor is coagulatedtotally.
展开▼
